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HomeEURL ECVAM progress report on the development, validation and regulatory acceptance of alternative methods (2010-2013)
Prepared in the framework of directive 76/768/EEC and regulation (EC) No 1223/2009 on cosmetic products
Meiteashonraí an fhoilseacháin
Provisions of Regulation No 1223/2009 on cosmetic products require that the European Commission reports on a yearly basis to the European Parliament and Council on the progress made in the development, validation and regulatory acceptance of alternative methods and on the compliance with the deadlines of the animal testing and marketing bans. This EURL ECVAM technical report provides an update since 2010 on the state of play of alternative methods for all the toxicological areas relevant to the Cosmetics Regulation and supplements the 2013 Commission Communication on the animal testing and marketing ban and on the state of play in relation to alternative methods in the field of cosmetics. Overall good progress has been made in the validation and regulatory acceptance in areas such as local toxicity where the underpinning science is more advanced and mature alternative methods are available. For very complex endpoints on the other hand, such as chronic systemic toxicity, carcinogenicity or reproductive toxicity , efforts are predominantly focused on research and development where the emphasis is on the integration of a variety of methods based on mechanistic understanding. The future is bright however, since considerable advances in new in vitro technologies, systems biology, bioinformatics and computational toxicology are driving a paradigm shift in toxicological testing and assessment where non-animal methods will ultimately become the tools of choice.
- Dáta foilsithe:
- Údar corparáideach/údair chorparáideacha: Institute for Health and Consumer Protection (An tAirmheán Comhpháirteach Taighde)
- Téamaí: Tionscal cógaisíochta agus cosmaideacha , Taighde eolaíoch agus teicniúil
- Ábhar: consumer protection , cosmetic product , directive (EU) , protection of animals , research and development , research method , research report
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| ISSN 1831-9424 | ISBN 978-92-79-29943-8 | DOI 10.2788/90736 | Uimhir chatalóige LB-NA-25981-EN-N |
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| ISSN 1018-5593 | ISBN 978-92-79-29944-5 | DOI 10.2788/90795 | Uimhir chatalóige LB-NA-25981-EN-C |
- Released on EU publications website:
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