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Systematic review on hepatitis B and C prevalence in the EU/EEA
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Systematic review on hepatitis B and C prevalence in the EU/EEA

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This systematic literature review was carried out to retrieve, assess and synthesise all available data published between 2005 and 2015 on the prevalence of hepatitis B and C in EU/EEA countries in the general population and the following subgroups: blood donors, pregnant women, people who inject drugs (PWID), men who have sex with men (MSM), prisoners and migrants. A search strategy was developed and a literature search performed. Publications of interest were first screened based on title and abstract. The full text of all publications selected during the title and abstract screening was then assessed for relevance. This was followed by extracting the relevant data from the final selected publications. Data from each study were extracted using a predefined set of variables covering study characteristics, study population details, prevalence of HBV and HCV markers (HBsAg and anti-HCV antibodies), including the type of sample that was collected and the type of laboratory test that was used. Finally, the risk of bias was assessed for each study and used to categorise the included studies according to quality indicators defined in the study design. To assess the prevalence of HBV and HCV among blood donors, PWID and migrants, alternative sources for data were used. These sources were the latest Council of Europe report on national blood donor data, data from the European Monitoring Centre for Drugs and Drug Addiction (EMCDDA) database and an ECDC systematic review entitled ‘Epidemiological assessment of hepatitis B and C among migrants in the EU/EEA’. An algorithm, which also took into account study quality, was used to develop a general population HBV and HCV prevalence estimate for each EU/EEA country, with the aim to estimate the current burden of chronic HBV and HCV in the EU/EEA.
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ISBN 978-92-9193-982-4
DOI 10.2900/24396
Kataloški broj TQ-02-16-837-EN-N
ISBN 978-92-9498-040-3
DOI 10.2900/930827
Kataloški broj TQ-02-16-837-EN-C
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ISSN ISBN 978-92-9193-982-4 DOI 10.2900/24396 Kataloški broj TQ-02-16-837-EN-N
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ISSN ISBN 978-92-9498-040-3 DOI 10.2900/930827 Kataloški broj TQ-02-16-837-EN-C
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