For a better user experience please update your browser or use Chrome or Firefox browser.
Utilitajiet
Publication detail
HomePreparation and certification of the porcine reference materials for contents (mass fractions) of chlortetracycline (CTC) based on HPLC
BCR-695 and -696 (pig liver), BCR-697 and -698 (pig muscle), BCR-706 and -707 (pig kidney)
Metadejta tal-pubblikazzjoni
This report describes the production and certification of chlortetracycline (CTC)-free and CTC-incurred pig tissues (kidney, liver and muscle) as reference materials. High performance liquid chromatography (HPLC) with fluorescence detection of CTC and 4-epi-CTC was used for all tissue analyses. A preliminary study was performed to optimise the production control. In the main study, 500 vials each of CTC-free and CTCincurred liver (BCR-695 and –696), kidney (BCR-697 and –698) and muscle (BCR-706 and –707) were produced. A stability study was performed over 79 weeks testing samples stored at -18, +4, 20 and 37 °C. No measurable degradation occurred over this time period at any of the storage temperatures. Further, homogeneity of the materials was tested, too. Certified values of the “blank materials” were based on the observed detection limit. Certified values for the CTC-positive materials are accompanied by a GUMcompliant uncertainty statement (coverage factor k = 2) [1] considering uncertainty contributions from the batch characterisation, homogeneity, stability as well as from the common calibrant used in the certification exercise.
- Ippubblikat:
- Awtur(i) korporattiv(i): L-Istitut tal-Materjali u l-Kejl ta’ Referenza (Iċ-Ċentru Konġunt tar-Riċerka)
- Awturi personali: Ginkel, L. A. van ; Juhel-Gaugain, M ; McEvoy, J. D. G
- Temi Tekonoloġija u sigurtà alimentari
- Suġġett: approvazzjoni , laħam tal-majjal , metodu ta’ riċerka , riċerka xjentifika , spezzjoni tal-ikel , spezzjoni veterinarja
|
Karta
|
|||
| ISSN | ISBN 92-894-3890-8 | DOI | Numru tal-Katalogu LA-NA-21-062-EN-C |
- Released on EU publications website:
Viżwalizzatur tad-dokument
Note:
Il-pubblikazzjoni ma tistax tintwera fil-viżwalizzatur tad-dokument. Verżjoni miftuħa fuq l-internet
Tista’ taċċessaha minn: Iddawnlowdjar u lingwi