Isolation and concentration of staphylococcal anatoxins from culture solutions. Standardization of developed procedures. Text automatically translated in your browsing language Automatically translated

The subject of the contract is the isolation and concentration of staphylococcal anatoxins from culture solutions together with standardization of developed procedures. As part of the service, the procuring entity requires the following sub-activities: The sponsor shall supply culture media containing anatoxins obtained as haemolysins during the cultivation of the above-mentioned vaccine bacterial staphylococcal strains. Specifically, the contract concerns inactivated haemolysine alfa, beta and, if present in the medium, delta. We require the development of technology for the isolation and purification of these anatoxins from the supplied culture media that contain them. The developed technology will be standardized and will be usable in any commercial production at the level of GMP requirements. (b) The service will also include the development of technology for concentrating isolated and purified, above mentioned, anatoxins. The technology of the anatoxin concentration process will be standardized and will be applicable in any commercial production at the level of GMP requirements. (c) The output of the service will be documentation for points (a), (b) and the design of methodologies for control tests applicable to quality control of these semi-finished products in production. Another output of the service will be the delivery of samples of concentrated anatoxins obtained under points (a), (b). For each anatoxin, 10 ml of concentrate with documentation will be supplied. Text automatically translated in your browsing language Automatically translated

73100000 - Research and experimental development services

92000000 - Recreational, cultural and sporting services CVP code deduced from the text of the procedure AI-generated