Opinion of Advocate General Bot delivered on 24 March 2011$

Opinion of Advocate General Bot delivered on 24 March 2011.#Etimine SA v Secretary of State for Work and Pensions.#Reference for a preliminary ruling from High Court of Justice (England & Wales), Queen's Bench Division (Administrative Court).#Environment and protection of human health – Directive 67/548/EEC –Regulation (EC) No 1272/2008 – Borate substances – Classification as reprotoxic substances in category 2 – Directive 2008/58/EC and Regulation (EC) No 790/2009 – Adaptation of the classifications to technical and scientific progress – Validity – Methods of assessing the intrinsic properties of those substances – Manifest error of assessment – Legal basis – Obligation to state reasons – Principle of proportionality.#Case C-15/10.